J.L.
Does she have a favorite animal? Blanket? My kids didn't really take to any animals that were given to them, but then I took them to pick out "special friends" that they could do anything with. My 4 year old is autistic and seemed to like the idea that he could talk to, throw, sleep with, or just play with his Zillow. They each picked their own animals and when they weren't playing with them I walked around with them in my shirt to put my scent on them. My second son, 3, really responded to that. They just need that safety item. My boys take their Zillow and Ibs with them when we travel and that helps with anxieties of new places as well.
Hope that helps! Good luck, this stage of the game is tricky and my heart goes out to you