E.B.
Hey it sounds like maybe night terror my son was stricken with it about that age as well. he was still sharing a room with us and he would be down just fine and fifteen minutes later he would scream and thrash in his sleep. his eyes would be wide open. she may not be that bad but she may have had a bad dream after she got her shots and now she is afraid to go to sleep and it is waking her at night...she could also be getting her back molars in if she doesnt have them already. those are my ideas...good luck hopefully things get back to normal for you really soon!!