I.G.
Uneven development is normal, most women do not have exactly same sized breasts and it is likely that the smaller breast will catch up, but never be completely even.
If you are concerned about her development you should take her to an OB/GYN first. It would be a good idea to build a rapport with one now, if she has her period she may want to start regular exams as well.
For the acne the GYN may recommend birth control pills or refer you to a dermatologist. Many people are hesitant to put their teenagers on the pill, however, if topical acne medications are not working for her (try prescription strength from dermatologist) I would consider it, as the pill as much less severe side effects than many systemic (oral) acne medications.
Good luck