M.E.
I'm 49 and was surprised so learn that there is a great deal of bias if you've been out of the work force for a period of time. I was in non-profit for 10 years and had risen to management level in a small non-profit. I left work for 10 years to raise my daughters. On a whim I decided to apply for a job with a Catholic school in their development office - doing database management - a job similar to what I had done during the middle of my career. I did not even get an interview. I eventually got a job with a former boss who knew and trusted my work and she is delighted with me. I've been working for 3 months and I was definitely behind in some of the software knowledge but I've gotten training and I feel almost completely up to speed and fairly confident that I bring a lot of experience and knowledge to the position despite being out of the workforce for a long time.
Recently, however, I heard a discussion on the radio about employers being reticent to hire people who are unemployed or those who have been unemployed for a while. In fact, a couple employers called the radio and said outright that they would not even interview someone who was unemployed. That shocked me! For you, I doubt it's your age but more than likely the fact that you have been out of work. In my situation, my current job is NOT at the same level as when I left my career - I am an assistant to a woman who is 20 years younger than me and has less experience than me. But I realized that I needed current experience and that's what I'm getting. Good-luck.