Vicky,
I also come from a large family. We get together every year and play a few games...it's really fun!
One game, we seperated into two teams. One team tied red balloons around their ankle (you want to leave them a little loose), the other team tied green balloons to their ankles. The host didn't play this one, she sat out in order to time it. The teams had about 2 minutes to go at each other and try to pop the other's balloon. So, while you're trying to pop their balloon with your feet, you're trying to keep yours from getting busted. We had SO much fun with that!
We also played one where you take a few small items and put them in seperate boxes. We had about 40 people at ours, so there was probably about 10 boxes with a small item (like a votive candle or something) inside. My cousin read this story and everytime she said the words left or lefty/right or righty, you sent the box to the left or right of you. When the story ended, whoever got a box got to keep the small gift. You could always do that with different gifts if your family is small enough and make sure that everyone has one. If you want to do that game (It's also a lot of fun). If you're interested, let me know and I will get the story and email it to you.
This last one is my FAVORITE!! It's called "Dirty Santa". JUST HEAR ME OUT...it's not bad, lol. Everyone takes a gift (the limit we have is $15). You bring the gift either in a bag or wrapped. Everyone draws a number. The first person goes and picks a gift (any gift) and opens it. The second person can either "steal" the first person's gift or get a new one. If they "steal" the gift instead of drawing a new one, the first person goes to the table and gets another gift. The third person has the option to "steal" the first person's gift, or the second person's gift or pick a new one. A gift can only be stolen 3 times and then it is officially retired and can no longer be stolen. We have played this game for the past three years and have had SO much fun! Women usually bring Christmas decorations and men usually bring small tools or things that they like to trade around so the guys aren't stuck getting something feminine. The older kids play this with us, the smaller children are just given some small gifts to play with instead of playing this game.
I hope this is helpful. Like I said, if you need the story I was talking about, I will be glad to get it and email it to you. Just let me know.
GOOD LUCK!!! :)