hi, J.,
I'm a psychologist and have a number of clients who have found Cymbalta helpful. having said that, different people will react differently to different drugs. Check out a reliable medical website such as www.webmed.com for info on side effects. Most people will adjust to a med within a few days. If not, ask your psychiatrist to change your med. If you are not seeing a psychiatrist, but were given the med by a general practitioner and/or didn't get enough discussion of the potential side effects or how long it would take to work, please think about seeing a psychiatrist who specializes in mood disorders such as depression and who can best monitor these types of drugs. I can't emphasize strongly enough how important it is to see a specialist when you are on these medications.
Also, depression impacts your life in many ways, and seeing a therapist to help with talking about your feelings and changes needed in your life can be hugely helpful, whether or not you take meds. Just wanted to mention this, just in case you hadn't considered it.
take care, S.