I use a hodge podge of curricula so I won't comment on that.
For homeschooling one or two while the others are in school, we do that.
I started with my then 5th grader. I told the other two that NO they were going to school, there was no reason to keep them home. My 8th grader didn't fight me on it and scoffed at my even attempting to homeschool her sister. My 2nd grader loved school so it was a non issue. My oldest, 19 at the time told me I was crazy, a freak, and would ruin her future.
That year went OK. I then pulled the next one out in third and did two at home. My then highschooler would have no part of it.
Now I still homeschool my 2 and one will go back into public school next year, she will be in highschool. My now 5th grader may go back, we are not sure yet.
I follow the vacation schedule of the public school. I find it too hard to have school for one or two when the other has a free day or week even. When my senior is off, the other two get a day off too. I do take vacations and breaks while she is in school though.
I do not follow the public school's curriculum.
It will work, be positive.