K.L.
After several frustrating years and expensive vet bills, including anti-anxiety medication (for the cat), changing our cat's litter to Dr. Elsey's Precious Cat "Cat Attract" Cat Litter has made a tremendous difference at our house. We were on the verge of confining our cat to a cage when we weren't in the same room with him because he'd started peeing on the hard-surfaced floor when he no longer had access to carpets or rugs.
I'd suggest you keep the cats out of the master bedroom until you have used a urine removal system. We haven't used Dr. Elsey's Precious Cat Urine Removal Program, but based on our experience with the litter, I'd recommend trying it.