We've flown many times, and have done it many ways. When I am by myself, I always take the stroller, never the car seat. Depending on the kind of car seat you have, it may or may not be FAA approved, so you definitely want to check that out before you go through the hassle. The stroller isn't only good for the kid, but also for the rest of the stuff. If he's walking, but the carry ons in the stroller so your hands are free. Without the car seat, he'll have a lot more room to move while still being in his seat. However, if you don't think he'll stay there for take off and landing, then you might need the seat. It's very wearing to have to carry it, though, even with a travel case. During turbulence, usually it's okay if he's in you lap as opposed to his own seat, but during landing and take off he would have to be in his seat. GL! I hope it goes well!