M.M.
Neither of my kids ever responded at all to Mylicon. What did the trick for us was a different gripe water called Colic Calm (you can get it at CVS or online). Worked wonders on both kids and helped them sleep quickly.
You may also want to switch to a sensitive or fussy formula. Neither of my kids did well with Similac for some reason. My son did better on regular old Enfamil, and my daughter needed the Gentlease (fussy and gassy) from Enfamil.
I would say just keep trying different formulas, and keep an eye out for reflux symptoms.